Examination of Candida Albicans in Saliva of Iraqi lichen Planus Patients

Abstract

Background: One to two percent of the population suffers from lichen planus, an inflammatory skin disorder that may affect almost every part of the body, including the nails, hair, and mucous membranes. Even though lichen planus  may present in a variety of ways, the most common sites of involvement are the skin and the mouth. A superinfection with Candida  species can worsen the symptoms of oral lichen planus, particularly in its erosive variants, where one of the most opportunistic mycosis globally is the Candida ssp and the research aims to evaluate the prevalences of candida albicans  in lichen planus patients (oral & skin)in comparison to healthy control group. Material and method: The sample consists of 90 subjects divided into 3 groups each of 30 as follow: oral lichen planus  group ,skin lichen planus group and  control healthy group. Saliva samples obtained from all subjects were cultivated on selective media (SDA) and colony forming unit per milliliter of Candida albicans was estimated after incubation at 37c for24- 48 h. Results: Results shows the prevelance of Candida albicans  as a proportion in "Oral L.P. and healthy control." groups, showed highly significant difference  while the  proportion in  "Oral L.P. and skin L.P  groups, results showed no significant difference and Finally, the proportion in  "Skin L.P. and Control" did not reveal any discernible variation . Conclusion: the prevalence of Candida albicans in  oral L.P with healthy control "showed highly significant difference  while comparing  "Oral L.P. and skin L.P." there was no  difference. Lastly, the "Skin L.P. and healthy Control", show  no differences between them.